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FISH System Overview

Our FISH System is used to detect and localize the presence of specific DNA sequences in chromosomes for an identification of chromosomal abnormalities.

FISH Probes and Imaging Analysis System

Probes

Our FISH probes are synthetic pieces of DNA that couple with a fluorescent indicator, so that the chromosomes or genes that they bind to can be directly visualized under our imaging analysis system.

FISH Imaging Analysis System

Our imaging analysis system is used for examining the labeled sample and checking the quality and quantity of the fluorescent signals where chromosomal abnormalities can be identified.

Operation Procedures

A brief description of the FISH procedure follows:

  1. A specific fluorescent labeled DNA probe is mixed with a patient’s fluid sample or tissue sample placed on a microscope slide. This step allows the DNA probe to hybridize with its complementary target DNA.
  2. Once hybridized, the fluorescent fragments on the probes will show precisely where their target DNA lies along a chromosome.
  3. Under the fluorescent microscope, the medical practitioner can examine the labeled sample, check the quality and quantity of the fluorescent signals and record the areas for analysis.
  4. The imaging analysis software then captures and saves the fluorescent images in the computer.