HPV-DNA Biosensor Chip is a label-free DNA chip for the diagnosis of HPV infection and genotyping of HPV. The HPV Chip can identify each of 24 distinctive common HPV genotypes, including 16 high-risk genotypes and 8 low-risk genotypes. The HPV Chip not only has high sensitivity and specificity, but also has short detection time. It can also identify mixed HPV infection and can be used to guide individual therapy and vaccination. The HPV Chip is expected to be used in the gynecology and dermatology departments of hospitals.

Characteristics of the HPV-DNA Biosensor Chip

1. High sensitivity and specificity
2. Short detection time
3. Label-free detection
4. Identify specific genotypes of HPV
5. Identify mixed HPV infections
6. Applications
1. Identify 24 genotypes of HPV (including CP8304 found primarily in China)
• 16 high-risk types 16, 18, 31,33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, cp8304
• 8 low-risk types 6, 11, 40, 42, 43, 44, 54, 70
2. Individualized therapy
3. HPV vaccination

What is HPV?

HPV is a common virus that infects the skin and mucous membranes of humans, causing various kinds of warts as well as cervical cancer. More than 100 types of HPV have been identified. While infection by most types of HPV are relatively harmless, some can cause skin or genital warts ("low-risk") and others can cause cervical cancer ("high-risk"). Almost all types of cervical cancer are associated with high-risk HPV infection. However, HPV tests available in the China market are insufficient in addressing clinical needs as they can only classify the virus into the high-risk or the low-risk category or have high false positive or negative rates in identifying specific HPV genotypes.